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Personalised intervention for people with depression and severe COPD.


ABSTRACT: Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.

SUBMITTER: Alexopoulos GS 

PROVIDER: S-EPMC3585422 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature

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Personalised intervention for people with depression and severe COPD.

Alexopoulos George S GS   Kiosses Dimitris N DN   Sirey Jo Anne JA   Kanellopoulos Dora D   Novitch Richard S RS   Ghosh Samiran S   Seirup Joanna K JK   Raue Patrick J PJ  

The British journal of psychiatry : the journal of mental science 20130207 3


Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive sympt  ...[more]

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