New and future immunomodulatory therapy in type 1 diabetes.
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ABSTRACT:
SUBMITTER: Tooley JE
PROVIDER: S-EPMC3586241 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Publications
New and future immunomodulatory therapy in type 1 diabetes.
Tooley James E JE Waldron-Lynch Frank F Herold Kevan C KC
Trends in molecular medicine 20120217 3
Type 1 diabetes is a common autoimmune disease that affects millions of people worldwide and has an incidence that is increasing at a striking rate, especially in young children. It results from the targeted self-destruction of the insulin-secreting β cells of the pancreas and requires lifelong insulin treatment. The effects of chronic hyperglycemia - the result of insulin deficiency - include secondary endorgan complications. Over the past two decades our increased understanding of the pathogen ...[more]
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