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Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics.


ABSTRACT: Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes - Dobrava, Kurkino, Saaremaa, and Sochi - that show characteristic differences in their phylogeny, specific host reservoirs, geographical distribution, and pathogenicity for humans.

SUBMITTER: Klempa B 

PROVIDER: S-EPMC3586401 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature

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Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics.

Klempa Boris B   Avsic-Zupanc Tatjana T   Clement Jan J   Dzagurova Tamara K TK   Henttonen Heikki H   Heyman Paul P   Jakab Ferenc F   Kruger Detlev H DH   Maes Piet P   Papa Anna A   Tkachenko Evgeniy A EA   Ulrich Rainer G RG   Vapalahti Olli O   Vaheri Antti A  

Archives of virology 20121023 3


Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes - Dobrava, Kurkino, Saaremaa, and Sochi - that show characteristic differences in their phylogeny, specific host reservoirs, geographical distribution, and pathogenicity for humans. ...[more]

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