Ontology highlight
ABSTRACT:
SUBMITTER: Nakata T
PROVIDER: S-EPMC3587191 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Nakata Tomohiro T Ishiguro Manabu M Aduma Nana N Izumi Hiroe H Kuroiwa Asato A
Proceedings of the National Academy of Sciences of the United States of America 20130211 9
Using a comprehensive transcriptome analysis, a Z chromosome-linked chicken homolog of hemogen (cHEMGN) was identified and shown to be specifically involved in testis differentiation in early chicken embryos. Hemogen [Hemgn in mice, EDAG (erythroid differentiation-associated gene protein) in humans] was recently characterized as a hematopoietic tissue-specific gene encoding a transcription factor that regulates the proliferation and differentiation of hematopoietic cells in mammals. In chicken, ...[more]