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Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa-hydro-quinoline-3-carboxyl-ate.

ABSTRACT: In the title mol-ecule, C24H28N2O3, the cyclo-hexene ring is in a sofa conformation and the 1,4-dihydro-pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63?(7)°. In the crystal, N-H?O hydrogen bonds connect the mol-ecules into C(6) chains parallel to the b axis and pairs of weak C-H?O hydrogen bonds link inversion-related chains into a ladder motif through R2(2)(18) rings. A weak intra-molecular C-H?O hydrogen bond is also observed.

SUBMITTER: Ozturk Yildirim S

PROVIDER: S-EPMC3588325 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa-hydro-quinoline-3-carboxyl-ate.

Oztürk Yildirim Sema S Butcher Ray J RJ Gündüz Miyase Gözde MG El-Khouly Ahmed A Simşek Rahime R Safak Cihat C

Acta crystallographica. Section E, Structure reports online 20121208 Pt 1

In the title mol-ecule, C24H28N2O3, the cyclo-hexene ring is in a sofa conformation and the 1,4-dihydro-pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N-H⋯O hydrogen bonds connect the mol-ecules into C(6) chains parallel to the b axis and pairs of weak C-H⋯O hydrogen bonds link inversion-related chains into a ladder motif through R2(2)(18) rings. A weak intra-molecular C-H⋯O hydrogen bon ...[more]

PMID: 23476426

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