Ontology highlight
ABSTRACT:
SUBMITTER: Jiang X
PROVIDER: S-EPMC3589105 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Jiang Xiaolong X Wang Guangfu G Lee Alice J AJ Stornetta Ruth L RL Zhu J Julius JJ
Nature neuroscience 20130113 2
Deciphering the interneuronal circuitry is central to understanding brain functions, yet it remains a challenging task in neurobiology. Using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-3) interneurons and L5 pyramidal neurons in the rat neocortex. L1 single-bouquet cells (SBCs) preferentially formed unidirectional inhibitory connections on L2/3 interneurons that inhibited ...[more]