Ontology highlight
ABSTRACT:
SUBMITTER: Kremer K
PROVIDER: S-EPMC3591302 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Kremer Katrin K Kamin Dirk D Rittweger Eva E Wilkes Jonathan J Flammer Halley H Mahler Sabine S Heng Joanne J Tonkin Christopher J CJ Langsley Gordon G Hell Stefan W SW Carruthers Vernon B VB Ferguson David J P DJ Meissner Markus M
PLoS pathogens 20130307 3
The basic organisation of the endomembrane system is conserved in all eukaryotes and comparative genome analyses provides compelling evidence that the endomembrane system of the last common eukaryotic ancestor (LCEA) is complex with many genes required for regulated traffic being present. Although apicomplexan parasites, causative agents of severe human and animal diseases, appear to have only a basic set of trafficking factors such as Rab-GTPases, they evolved unique secretory organelles (micro ...[more]