Ontology highlight
ABSTRACT:
SUBMITTER: Martini P
PROVIDER: S-EPMC3592432 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Martini Paolo P Sales Gabriele G Massa M Sofia MS Chiogna Monica M Romualdi Chiara C
Nucleic acids research 20120921 1
Gene set analysis using biological pathways has become a widely used statistical approach for gene expression analysis. A biological pathway can be represented through a graph where genes and their interactions are, respectively, nodes and edges of the graph. From a biological point of view only some portions of a pathway are expected to be altered; however, few methods using pathway topology have been proposed and none of them tries to identify the signal paths, within a pathway, mostly involve ...[more]