Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4).

ABSTRACT: We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.

SUBMITTER: Cress BF 

PROVIDER: S-EPMC3593321 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature