Ontology highlight
ABSTRACT:
SUBMITTER: Kay BP
PROVIDER: S-EPMC3593969 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Kay Benjamin P BP DiFrancesco Mark W MW Privitera Michael D MD Gotman Jean J Holland Scott K SK Szaflarski Jerzy P JP
Epilepsia 20130107 3
<h4>Purpose</h4>Idiopathic generalized epilepsy (IGE) resistant to treatment is common, but its neuronal correlates are not entirely understood. Therefore, the aim of this study was to examine resting-state default mode network (DMN) functional connectivity in patients with treatment-resistant IGE.<h4>Methods</h4>Treatment resistance was defined as continuing seizures despite an adequate dose of valproic acid (valproate, VPA). Data from 60 epilepsy patients and 38 healthy controls who underwent ...[more]