Efficacy and safety of transarterial radioembolization versus chemoembolization in patients with hepatocellular carcinoma.

ABSTRACT:

Purpose

Intermediate-stage hepatocellular carcinoma (HCC) is usually treated with locoregional therapy using transarterial chemoembolization (TACE). Transarterial radioembolization (TARE) using β-emitting yttrium-90 integral to the glass matrix of the microspheres is an alternative to TACE. This retrospective case-control study compared the outcomes and safety of TARE versus TACE in patients with unresectable HCC.

Materials and methods

Patients with unresectable HCC without portal vein thrombosis treated with TARE between 2005 and 2008 (n = 61) were retrospectively frequency-matched by age, sex, and liver dysfunction with TACE-treated patients (n = 55) in the Mayo Clinic Hepatobiliary Neoplasia Registry. Imaging studies were reviewed, and clinical and safety outcomes were ab

SUBMITTER: Moreno-Luna LE 

PROVIDER: S-EPMC3594060 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature