Ontology highlight
ABSTRACT:
SUBMITTER: Hoeijmakers WA
PROVIDER: S-EPMC3594968 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Hoeijmakers Wieteke A M WA Salcedo-Amaya Adriana M AM Smits Arne H AH Françoijs Kees-Jan KJ Treeck Moritz M Gilberger Tim-Wolf TW Stunnenberg Hendrik G HG Bártfai Richárd R
Molecular microbiology 20130128 5
Histone variants are key components of the epigenetic code and evolved to perform specific functions in transcriptional regulation, DNA repair, chromosome segregation and other fundamental processes. Although variants for histone H2A and H3 are found throughout the eukaryotic kingdom, variants of histone H2B and H4 are rarely encountered. H2B.Z is one of those rare H2B variants and is apicomplexan-specific. Here we show that in Plasmodium falciparum H2B.Z localizes to euchromatic intergenic regi ...[more]