Ontology highlight
ABSTRACT:
SUBMITTER: Rodrigo G
PROVIDER: S-EPMC3595027 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Rodrigo Guillermo G Elena Santiago F SF
Genome biology and evolution 20130101 1
Robustness is considered a ubiquitous property of living systems at all levels of organization, and small noncoding RNA (sncRNA) is a genuine model for its study at the molecular level. In this communication, we question whether microRNA precursors (pre-miRNAs) are actually structurally robust, as previously suggested. We found that natural pre-miRNAs are not more robust than expected under an appropriate null model. On the contrary, we found that eukaryotic pre-miRNAs show a significant enrichm ...[more]