Ontology highlight
ABSTRACT:
SUBMITTER: Jiang RH
PROVIDER: S-EPMC3595378 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Jiang Rays H Y RH Stahelin Robert V RV Bhattacharjee Souvik S Haldar Kasturi K
Trends in microbiology 20130130 3
Similar to bacteria, eukaryotic pathogens may utilize common strategies of pathogenic secretion, because effector proteins from the oomycete Phytophthora infestans and virulence determinants from the human malaria parasite Plasmodium falciparum share a functionally equivalent host-cell-targeting motif (RxLR-dEER in P. infestans and RxLxE/D/Q in P. falciparum). Here we summarize recent studies that reveal that the malarial motif may function differently than previously envisioned. Binding of the ...[more]