Dataset Information

Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study.

ABSTRACT:

Background

Few emergency department (ED) evaluations on acute lung injury (ALI) have been carried out; hence, we sought to describe a cohort of hospitalized ED patients at risk for ALI development.

Methods

Patients presenting to the ED with at least one predisposing condition to ALI were included in this study, a subgroup analysis of a multicenter observational cohort study (USCIITG-LIPS 1). Patients who met ALI criteria within 6 h of initial ED assessment, received end-of-life care, or were readmitted during the study period were excluded. Primary outcome was frequency of ALI development; secondary outcomes were ICU and hospital mortality.

Results

Twenty-two hospitals enrolled 4,361 patients who were followed from the ED to hospital discharge. ALI developed in 303 (7.0 %) patients at a median onset of 2 days (IQR 2-5). Of the predisposing conditions, frequency of ALI development was highest in patients who had aortic surgery (43 %) and lowest in patients with pancreatitis (2.8 %). Compared to patients who did not develop ALI, those who did had higher ICU (24 % vs. 3.0 %, p?ConclusionsSeven percent of hospitalized ED patients with at least one predisposing condition developed ALI. The frequency of ALI development varied significantly according to predisposing conditions and across institutions. Further research is warranted to determine the factors contributing to ALI development.

SUBMITTER: Hou PC

PROVIDER: S-EPMC3598496 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature

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Publications

Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study.

Hou Peter C PC Elie-Turenne Marie-Carmelle MC Mitani Aya A Barry Jonathan M JM Kao Erica Y EY Cohen Jason E JE Frendl Gyorgy G Gajic Ognjen O Gentile Nina T NT

International journal of emergency medicine 20120527 1

<h4>Background</h4>Few emergency department (ED) evaluations on acute lung injury (ALI) have been carried out; hence, we sought to describe a cohort of hospitalized ED patients at risk for ALI development.<h4>Methods</h4>Patients presenting to the ED with at least one predisposing condition to ALI were included in this study, a subgroup analysis of a multicenter observational cohort study (USCIITG-LIPS 1). Patients who met ALI criteria within 6 h of initial ED assessment, received end-of-life ca ...[more]

PMID: 22632126

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Dataset Information

Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study.

Background

Methods

Results

Publications

Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study.

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