Dataset Information

High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.

ABSTRACT: Comparative genomics is a formidable tool to identify functional elements throughout a genome. In the past ten years, studies in the budding yeast Saccharomyces cerevisiae and a set of closely related species have been instrumental in showing the benefit of analyzing patterns of sequence conservation. Increasing the number of closely related genome sequences makes the comparative genomics approach more powerful and accurate.Here, we report the genome sequence and analysis of Saccharomyces arboricolus, a yeast species recently isolated in China, that is closely related to S. cerevisiae. We obtained high quality de novo sequence and assemblies using a combination of next generation sequencing technologies, established the phylogenetic position of this species and considered its phenotypic profile under multiple environmental conditions in the light of its gene content and phylogeny.We suggest that the genome of S. arboricolus will be useful in future comparative genomics analysis of the Saccharomyces sensu stricto yeasts.

SUBMITTER: Liti G

PROVIDER: S-EPMC3599269 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.

Liti Gianni G Nguyen Ba Alex N AN Blythe Martin M Müller Carolin A CA Bergström Anders A Cubillos Francisco A FA Dafhnis-Calas Felix F Khoshraftar Shima S Malla Sunir S Mehta Neel N Siow Cheuk C CC Warringer Jonas J Moses Alan M AM Louis Edward J EJ Nieduszynski Conrad A CA

BMC genomics 20130131

<h4>Background</h4>Comparative genomics is a formidable tool to identify functional elements throughout a genome. In the past ten years, studies in the budding yeast Saccharomyces cerevisiae and a set of closely related species have been instrumental in showing the benefit of analyzing patterns of sequence conservation. Increasing the number of closely related genome sequences makes the comparative genomics approach more powerful and accurate.<h4>Results</h4>Here, we report the genome sequence a ...[more]

PMID: 23368932

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Dataset Information

High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.

Publications

High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.

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