Genome-wide analysis in chicken reveals that local levels of genetic diversity are mainly governed by the rate of recombination.

ABSTRACT:

Background

Polymorphism is key to the evolutionary potential of populations. Understanding which factors shape levels of genetic diversity within genomes forms a central question in evolutionary genomics and is of importance for the possibility to infer episodes of adaptive evolution from signs of reduced diversity. There is an on-going debate on the relative role of mutation and selection in governing diversity levels. This question is also related to the role of recombination because recombination is expected to indirectly affect polymorphism via the efficacy of selection. Moreover, recombination might itself be mutagenic and thereby assert a direct effect on diversity levels.

Results

We used whole-genome re-sequencing data from domestic chicken (broiler and layer breeds)

SUBMITTER: Mugal CF 

PROVIDER: S-EPMC3600008 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature