Ontology highlight
ABSTRACT:
SUBMITTER: Van Nieuwenhove L
PROVIDER: S-EPMC3600074 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Tropical medicine & international health : TM & IH 20130104 4
<h4>Objective</h4>To evaluate the accuracy of a peptide, corresponding to the variant surface glycoprotein (VSG) LiTat 1.5 amino acid (AA) sequence 268-281 and identified through alignment of monoclonal antibody selected mimotopes, for diagnosis of Trypanosoma brucei gambiense sleeping sickness.<h4>Methods</h4>A synthetic biotinylated peptide (peptide 1.5/268-281), native VSG LiTat 1.3 and VSG LiTat 1.5 were tested in an indirect ELISA with 102 sera from patients with HAT and 102 endemic HAT-neg ...[more]