Ontology highlight
ABSTRACT:
SUBMITTER: Presolski SI
PROVIDER: S-EPMC3600097 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Presolski Stanislav I SI Mamidyala Sreeman K SK Manzenrieder Florian F Finn M G MG
ACS combinatorial science 20120904 10
The copper-catalyzed azide-alkyne cycloaddition click reaction is a valuable process for the synthesis of libraries of drug candidates, derivatized polymers and materials, and a wide variety of other functional molecules. In some circumstances, the removal of the copper catalyst is both necessary and inconvenient. We describe here two immobilized forms of a Cu-binding ligand that has been shown to accelerate triazole formation under many different conditions, using different resin supports that ...[more]