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Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of o-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones.


ABSTRACT: An efficient and simple route to biologically and pharmaceutically important o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed utilizing readily available carboxylic acids and commercially available o-(trimethylsilyl)aryl triflates.

SUBMITTER: Dubrovskiy AV 

PROVIDER: S-EPMC3600654 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

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Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis of <i>o</i>-Hydroxyaryl Ketones, Xanthones, 4-Chromanones, and Flavones.

Dubrovskiy Anton V AV   Larock Richard C RC  

Tetrahedron 20130204 13


An efficient and simple route to biologically and pharmaceutically important <i>o</i>-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed utilizing readily available carboxylic acids and commercially available <i>o</i>-(trimethylsilyl)aryl triflates. ...[more]

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