Ontology highlight
ABSTRACT:
SUBMITTER: Jurisch-Yaksi N
PROVIDER: S-EPMC3601348 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Jurisch-Yaksi Nathalie N Rose Applonia J AJ Lu Huiqi H Raemaekers Tim T Munck Sebastian S Baatsen Pieter P Baert Veerle V Vermeire Wendy W Scales Suzie J SJ Verleyen Daphne D Vandepoel Roel R Tylzanowski Przemko P Yaksi Emre E de Ravel Thomy T Yost H Joseph HJ Froyen Guy G Arrington Cammon B CB Annaert Wim W
The Journal of cell biology 20130311 6
Cilia project from the surface of most vertebrate cells and are important for several physiological and developmental processes. Ciliary defects are linked to a variety of human diseases, named ciliopathies, underscoring the importance of understanding signaling pathways involved in cilia formation and maintenance. In this paper, we identified Rer1p as the first endoplasmic reticulum/cis-Golgi-localized membrane protein involved in ciliogenesis. Rer1p, a protein quality control receptor, was hig ...[more]