Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model.
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ABSTRACT:
SUBMITTER: Ghosh SP
PROVIDER: S-EPMC3601576 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Publications
Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model.
Ghosh Sanchita P SP Singh Rajbir R Chakraborty Kushal K Kulkarni Shilpa S Uppal Arushi A Luo Yue Y Kaur Prabhjit P Pathak Rupak R Kumar K Sree KS Hauer-Jensen Martin M Cheema Amrita K AK
Molecular bioSystems 20130213 4
Exposure to ionizing radiation (IR) elicits a set of complex biological responses involving gene expression and protein turnover that ultimately manifest as dysregulation of metabolic processes representing the cellular phenotype. Although radiation biomarkers have been reported in urine and serum, they are not informative about IR mediated tissue or organ specific injury. In the present study we report IR induced metabolic changes in gastrointestinal (GI) tissue of CD2F1 mice using ultra-perfor ...[more]
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