Ontology highlight
ABSTRACT:
SUBMITTER: Neumann H
PROVIDER: S-EPMC3602426 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Neumann Helmut H Günther Claudia C Vieth Michael M Grauer Martin M Wittkopf Nadine N Mudter Jonas J Becker Christoph C Schoerner Christoph C Atreya Raja R Neurath Markus F MF
PloS one 20130319 3
<h4>Background</h4>Clostridium difficile infection (CDI) is one of the most dreaded causes of hospital-acquired diarrhea. Main objective was to investigate whether confocal laser endomicroscopy (CLE) has the capability for in vivo diagnosis of C. difficile associated histological changes. Second objective was to prove the presence of intramucosal bacteria using CLE.<h4>Methods</h4>80 patients were prospectively included, 10 patients were diagnosed with CDI based on toxigenic culture. To validate ...[more]