Ontology highlight
ABSTRACT:
SUBMITTER: Farrer RA
PROVIDER: S-EPMC3604800 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Farrer Rhys A RA Henk Daniel A DA MacLean Dan D Studholme David J DJ Fisher Matthew C MC
Scientific reports 20130101
Sequence alignments form the basis for many comparative and population genomic studies. Alignment tools provide a range of accuracies dependent on the divergence between the sequences and the alignment methods. Despite widespread use, there is no standard method for assessing the accuracy of a dataset and alignment strategy after resequencing. We present a framework and tool for determining the overall accuracies of an input read dataset, alignment and SNP-calling method providing an isolate in ...[more]