Recursive partitioning analysis for the prediction of stereotactic radiosurgery brain metastases lesion control.

ABSTRACT:

Purpose

The objective of this investigation was to identify independent pretreatment factors that predict for control of local brain metastases (BM) in a large single-institution series of patients receiving stereotactic radiosurgery (SRS). Recursive partitioning analysis was used to potentially identify a class of patients with durable lesion control characteristics.

Methods

A retrospective SRS database containing baseline characteristics, treatment details, and follow-up data of newly diagnosed patients with 1-3 BM (on magnetic resonance imaging) treated with linear accelerator-based SRS was created. Three study endpoints were used: time to progression (primary endpoint, individual lesion progression; n = 536), time to first progression (secondary endpoint, first lesion pr

SUBMITTER: Rodrigues G 

PROVIDER: S-EPMC3607531 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature