Ontology highlight
ABSTRACT:
SUBMITTER: Grosmark AD
PROVIDER: S-EPMC3608095 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Grosmark Andres D AD Mizuseki Kenji K Pastalkova Eva E Diba Kamran K Buzsáki György G
Neuron 20120901 6
Sleep is composed of an alternating sequence of REM and non-REM episodes, but their respective roles are not known. We found that the overall firing rates of hippocampal CA1 neurons decreased across sleep concurrent with an increase in the recruitment of neuronal spiking to brief "ripple" episodes, resulting in a net increase in neural synchrony. Unexpectedly, within non-REM episodes, overall firing rates gradually increased together with a decrease in the recruitment of spiking to ripples. The ...[more]