Ontology highlight
ABSTRACT:
SUBMITTER: Bernal-Quiros M
PROVIDER: S-EPMC3608554 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bernal-Quirós Manuel M Wu Ying-Yu YY Alarcón-Riquelme Marta E ME Castillejo-López Casimiro C
PloS one 20130326 3
The B cell adaptor protein with ankyrin repeats (BANK1) and the B lymphoid tyrosine kinase (BLK) have been genetically associated with autoimmunity. The proteins of these genes interact physically and work in concert during B-cell signaling. Little is know about their interactions with other B-cell signaling molecules or their role in the process. Using yeast two hybrid (Y2H) we sought for factors that interact with BANK1. We found that the molecular switch PLCg2 interacts with BANK1 and that th ...[more]