Ontology highlight
ABSTRACT:
SUBMITTER: Wang K
PROVIDER: S-EPMC3614162 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Wang Ke K Shi Zhubing Z Zhang Min M Cheng Dianlin D
Acta crystallographica. Section F, Structural biology and crystallization communications 20130328 Pt 4
Proliferating cell nuclear antigen (PCNA) plays essential roles in DNA replication, DNA repair, cell-cycle regulation and chromatin metabolism. The PCNA from Drosophila melanogaster (DmPCNA) was purified and crystallized. The crystal of DmPCNA diffracted to 2.0 Å resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 Å. The structure of DmPCNA was determined by molecular replacement. DmPCNA forms a symmetric homotrimer in a head-to-tail manner. An interdom ...[more]