Genetic diversity of Toll-like receptor 5 among pig populations.
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ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC3615523 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
Genetic diversity of Toll-like receptor 5 among pig populations.
Yang Xiuqin X Li Haitao H Guan Qingzhi Q Liu Di D
Genetics and molecular biology 20130304 1
The Toll-like receptor 5 (TLR5) recognizes flagellin of Gram-positive and -negative bacteria and plays an important role in the host defense system. Here, we surveyed single nucleotide polymorphisms (SNPs) in the coding sequence of the porcine TLR5 gene in 83 individuals from five pig breeds, these including Chinese local populations and Western commercial pig breeds. A total of 19 medium polymorphic SNPs (0.25 < PIC < 0.5) were identified, three of which were missense mutations that clustered w ...[more]
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