Ontology highlight
ABSTRACT:
SUBMITTER: Duan Q
PROVIDER: S-EPMC3615534 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Duan Q Q Kou Y Y Clark N R NR Gordonov S S Ma'ayan A A
CPT: pharmacometrics & systems pharmacology 20130327
Genome-wide expression data from tumors and cell lines in breast cancer, together with drug response of cell lines, open prospects for integrative analyses that can lead to better personalized therapy. Drug responses and expression data collected from cell lines and tumors were used to generate tripartite networks connecting clusters of patients to cell lines and cell lines to drugs, to connect drugs to patients. Various approaches were applied to connect cell lines to tumor clusters: a standard ...[more]