Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC3616673 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Liu Hongliang H Wang Li-E LE Liu Zhensheng Z Chen Wei V WV Amos Christopher I CI Lee Jeffrey E JE Iles Mark M MM Law Matthew H MH Barrett Jennifer H JH Montgomery Grant W GW Taylor John C JC MacGregor Stuart S Cust Anne E AE Newton Bishop Julia A JA Hayward Nicholas K NK Bishop D Timothy DT Mann Graham J GJ Affleck Paul P Wei Qingyi Q
Carcinogenesis 20130104 4
Genome-wide association studies (GWASs) have mainly focused on top significant single nucleotide polymorphisms (SNPs), most of which did not have clear biological functions but were just surrogates for unknown causal variants. Studying SNPs with modest association and putative functions in biologically plausible pathways has become one complementary approach to GWASs. To unravel the key roles of mitogen-activated protein kinase (MAPK) pathways in cutaneous melanoma (CM) risk, we re-evaluated the ...[more]