Ontology highlight
ABSTRACT:
SUBMITTER: Ivanov M
PROVIDER: S-EPMC3616706 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Ivanov Maxim M Kals Mart M Kacevska Marina M Metspalu Andres A Ingelman-Sundberg Magnus M Milani Lili L
Nucleic acids research 20130115 6
DNA methylation is one of the most important epigenetic alterations involved in the control of gene expression. Bisulfite sequencing of genomic DNA is currently the only method to study DNA methylation patterns at single-nucleotide resolution. Hence, next-generation sequencing of bisulfite-converted DNA is the method of choice to investigate DNA methylation profiles at the genome-wide scale. Nevertheless, whole genome sequencing for analysis of human methylomes is expensive, and a method for tar ...[more]