Ontology highlight
ABSTRACT:
SUBMITTER: Koutros S
PROVIDER: S-EPMC3617165 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Koutros Stella S Berndt Sonja I SI Hughes Barry Kathryn K Andreotti Gabriella G Hoppin Jane A JA Sandler Dale P DP Yeager Meredith M Burdett Laurie A LA Yuenger Jeffrey J Alavanja Michael C R MC Beane Freeman Laura E LE
PloS one 20130404 4
Uncovering SNP (single nucleotide polymorphisms)-environment interactions can generate new hypotheses about the function of poorly characterized genetic variants and environmental factors, like pesticides. We evaluated SNP-environment interactions between 30 confirmed prostate cancer susceptibility loci and 45 pesticides and prostate cancer risk in 776 cases and 1,444 controls in the Agricultural Health Study. We used unconditional logistic regression to estimate odds ratios (ORs) and 95% confid ...[more]