Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.
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ABSTRACT:
SUBMITTER: Xing R
PROVIDER: S-EPMC3617494 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Publications
Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.
Xing Ruijun R Zhang Fan F Xie Jin J Aronova Maria M Zhang Guofeng G Guo Ning N Huang Xinglu X Sun Xiaolian X Liu Gang G Bryant L Henry LH Bhirde Ashwinkumar A Liang Amy A Hou Yanglong Y Leapman Richard D RD Sun Shouheng S Chen Xiaoyuan X
Nanoscale 20111107 12
We report in this communication a simple, facile surface modification strategy to transfer hydrophobic manganese oxide nanoparticles (MONPs) into water by using polyaspartic acid (PASP). We systematically investigated the effect of the size of PASP-MONPs on MRI of normal liver and found that the particles with a core size of 10 nm exhibited greater enhancement than those with larger core sizes. ...[more]
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