Ontology highlight
ABSTRACT:
SUBMITTER: Crisalli P
PROVIDER: S-EPMC3618716 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Crisalli Pete P Kool Eric T ET
Organic letters 20130311 7
Anthranilic acids were recently reported as superior catalysts for hydrazone and oxime formation compared to aniline, the classic catalyst for these reactions. Here, alternative proton donors were examined with varied pKa in an effort to enhance activity at biological pH. The experiments show that 2-aminobenzenephosphonic acids are superior to anthranilic acids in catalyzing hydrazone formation with common aldehyde substrates. ...[more]