Ontology highlight
ABSTRACT:
SUBMITTER: Colombo N
PROVIDER: S-EPMC3619076 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Colombo N N McMeekin D S DS Schwartz P E PE Sessa C C Gehrig P A PA Holloway R R Braly P P Matei D D Morosky A A Dodion P F PF Einstein M H MH Haluska F F
British journal of cancer 20130212 5
<h4>Background</h4>This open-label, multicentre, phase 2 trial evaluated the efficacy and tolerability of the mammalian target of rapamycin inhibitor ridaforolimus in women with advanced endometrial cancer.<h4>Methods</h4>Women with measurable recurrent or persistent endometrial cancer and documented disease progression were treated with ridaforolimus 12.5 mg intravenously once daily for 5 consecutive days every 2 weeks in a 4-week cycle. The primary end point was clinical benefit response, defi ...[more]