Nicotine withdrawal modulates frontal brain function during an affective Stroop task.

ABSTRACT:

Background

Among nicotine-dependent smokers, smoking abstinence disrupts multiple cognitive and affective processes including conflict resolution and emotional information processing (EIP). However, the neurobiological basis of abstinence effects on resolving emotional interference on cognition remains largely uncharacterized. In this study, functional magnetic resonance imaging (fMRI) was used to investigate smoking abstinence effects on emotion-cognition interactions.

Methods

Smokers (n = 17) underwent fMRI while performing an affective Stroop task (aST) over two sessions: once following 24-h abstinence and once following smoking as usual. The aST includes trials that serially present incongruent or congruent numerical grids bracketed by neutral or negative emotional distr

SUBMITTER: Froeliger B 

PROVIDER: S-EPMC3619410 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature