Ontology highlight
ABSTRACT:
SUBMITTER: Peresi E
PROVIDER: S-EPMC3619634 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Peresi Eliana E Oliveira Larissa Ragozo Cardoso LR da Silva Weber Laurentino WL da Costa Erika Alessandra Pellison Nunes EA Araujo João Pessoa JP Ayres Jairo Aparecido JA Fortes Maria Rita Parise MR Graviss Edward A EA Pereira Ana Carla AC Calvi Sueli Aparecida SA
Tuberculosis research and treatment 20130327
Cytokines play an essential role during active tuberculosis disease and cytokine genes have been described in association with altered cytokine levels. Therefore, the aim of this study was to verify if IFNG, IL12B, TNF, IL17A, IL10, and TGFB1 gene polymorphisms influence the immune response of Brazilian patients with pulmonary tuberculosis (PTB) at different time points of antituberculosis treatment (T1, T2, and T3). Our results showed the following associations: IFNG +874 T allele and IFNG +210 ...[more]