Ontology highlight
ABSTRACT:
SUBMITTER: Bossert JM
PROVIDER: S-EPMC3622847 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Bossert Jennifer M JM Stern Anna L AL
Addiction biology 20121212 3
In rats, reexposure to heroin-paired contexts after extinction of lever responding in a different context reinstates heroin seeking. Previous reports indicate that ventral hippocampus/Ca1 region plays a critical role in cocaine-, cue- and context-induced reinstatement of cocaine seeking. Here, we examined whether ventral subiculum, the output region of ventral hippocampus, is involved in context-induced reinstatement of heroin seeking. We found that reversible inactivation of ventral subiculum, ...[more]