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Perspectives and opportunities for nanomedicine in the management of atherosclerosis.


ABSTRACT: The use of nanotechnology for medical purposes--nanomedicine--has grown exponentially over the past few decades. This is exemplified by the US Food and Drug Administration's approval of several nanotherapies for various conditions, as well as the funding of nanomedical programmes worldwide. Although originally the domain of anticancer therapy, recent advances have illustrated the considerable potential of nanomedicine in the diagnosis and treatment of atherosclerosis. This Review elaborates on nanoparticle-targeting concepts in atherosclerotic disease, provides an overview of the use of nanomedicine in atherosclerosis, and discusses potential future applications and clinical benefits.

SUBMITTER: Lobatto ME 

PROVIDER: S-EPMC3623275 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Perspectives and opportunities for nanomedicine in the management of atherosclerosis.

Lobatto Mark E ME   Fuster Valentin V   Fayad Zahi A ZA   Mulder Willem J M WJ  

Nature reviews. Drug discovery 20111021 11


The use of nanotechnology for medical purposes--nanomedicine--has grown exponentially over the past few decades. This is exemplified by the US Food and Drug Administration's approval of several nanotherapies for various conditions, as well as the funding of nanomedical programmes worldwide. Although originally the domain of anticancer therapy, recent advances have illustrated the considerable potential of nanomedicine in the diagnosis and treatment of atherosclerosis. This Review elaborates on n  ...[more]

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