Genome-wide association studies in mice.
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ABSTRACT:
SUBMITTER: Flint J
PROVIDER: S-EPMC3625632 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Publications
Genome-wide association studies in mice.
Flint Jonathan J Eskin Eleazar E
Nature reviews. Genetics 20121009 11
Genome-wide association studies (GWASs) have transformed the field of human genetics and have led to the discovery of hundreds of genes that are implicated in human disease. The technological advances that drove this revolution are now poised to transform genetic studies in model organisms, including mice. However, the design of GWASs in mouse strains is fundamentally different from the design of human GWASs, creating new challenges and opportunities. This Review gives an overview of the novel s ...[more]
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