Aggregated gas molecules: toxic to protein?
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ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC3627187 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Aggregated gas molecules: toxic to protein?
Zhang Meng M Zuo Guanghong G Chen Jixiu J Gao Yi Y Fang Haiping H
Scientific reports 20130101
The biological toxicity of high levels of breathing gases has been known for centuries, but the mechanism remains elusive. Earlier work mainly focused on the influences of dispersed gas molecules dissolved in water on biomolecules. However, recent studies confirmed the existence of aggregated gas molecules at the water-solid interface. In this paper, we have investigated the binding preference of aggregated gas molecules on proteins with molecular dynamics simulations, using nitrogen (N₂) gas an ...[more]
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