Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC.
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ABSTRACT:
SUBMITTER: Harrison EM
PROVIDER: S-EPMC3628104 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
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Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC.
Harrison Ewan M EM Paterson Gavin K GK Holden Matthew T G MT Larsen Jesper J Stegger Marc M Larsen Anders Rhod AR Petersen Andreas A Skov Robert L RL Christensen Judit Marta JM Bak Zeuthen Anne A Heltberg Ole O Harris Simon R SR Zadoks Ruth N RN Parkhill Julian J Peacock Sharon J SJ Holmes Mark A MA
EMBO molecular medicine 20130325 4
Several methicillin-resistant Staphylococcus aureus (MRSA) lineages that carry a novel mecA homologue (mecC) have recently been described in livestock and humans. In Denmark, two independent human cases of mecC-MRSA infection have been linked to a livestock reservoir. We investigated the molecular epidemiology of the associated MRSA isolates using whole genome sequencing (WGS). Single nucleotide polymorphisms (SNP) were defined and compared to a reference genome to place the isolates into a phyl ...[more]
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