Ontology highlight
ABSTRACT:
SUBMITTER: Rodrigues R
PROVIDER: S-EPMC3629138 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Rodrigues Raquel R Grosso Ana Rita AR Moita Luís L
PloS one 20130417 4
The immune system relies on the plasticity of its components to produce appropriate responses to frequent environmental challenges. Dendritic cells (DCs) are critical initiators of innate immunity and orchestrate the later and more specific adaptive immunity. The generation of diversity in transcriptional programs is central for effective immune responses. Alternative splicing is widely considered a key generator of transcriptional and proteomic complexity, but its role has been rarely addressed ...[more]