Ontology highlight
ABSTRACT:
SUBMITTER: Kouyoumdjian H
PROVIDER: S-EPMC3629742 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Kouyoumdjian Hovig H Zhu David C DC El-Dakdouki Mohammad H MH Lorenz Kelly K Chen Jianjun J Li Wei W Huang Xuefei X
ACS chemical neuroscience 20130116 4
The development of a noninvasive method for the detection of Alzheimer's disease is of high current interest, which can be critical in early diagnosis and in guiding treatment of the disease. The aggregates of β-amyloid are a pathological hallmark of Alzheimer's disease. Carbohydrates such as gangliosides have been shown to play significant roles in initiation of amyloid aggregation. Herein, we report a biomimetic approach using superparamagnetic iron oxide glyconanoparticles to detect β-amyloid ...[more]