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A synergistically enhanced T(1) -T(2) dual-modal contrast agent.


ABSTRACT: Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC3634350 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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A synergistically enhanced T(1) -T(2) dual-modal contrast agent.

Zhou Zijian Z   Huang Dengtong D   Bao Jianfeng J   Chen Qiaoli Q   Liu Gang G   Chen Zhong Z   Chen Xiaoyuan X   Gao Jinhao J  

Advanced materials (Deerfield Beach, Fla.) 20120913 46


Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors. ...[more]

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