Ontology highlight
ABSTRACT:
SUBMITTER: Kahn SE
PROVIDER: S-EPMC3634618 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Kahn S E SE Suvag S S Wright L A LA Utzschneider K M KM
Diabetes, obesity & metabolism 20121001
An interaction between genes and the environment is a critical component underlying the pathogenesis of the hyperglycaemia of type 2 diabetes. The development of more sophisticated techniques for studying gene variants and for analysing genetic data has led to the discovery of some 40 genes associated with type 2 diabetes. Most of these genes are related to changes in β-cell function, with a few associated with decreased insulin sensitivity and obesity. Interestingly, using quantitative traits b ...[more]