Ontology highlight
ABSTRACT:
SUBMITTER: Kozlowski C
PROVIDER: S-EPMC3634668 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Kozlowski Cleopatra C Jeet Surinder S Beyer Joseph J Guerrero Steve S Lesch Justin J Wang Xiaoting X Devoss Jason J Diehl Lauri L
Disease models & mechanisms 20130410 3
The DSS (dextran sulfate sodium) model of colitis is a mouse model of inflammatory bowel disease. Microscopic symptoms include loss of crypt cells from the gut lining and infiltration of inflammatory cells into the colon. An experienced pathologist requires several hours per study to score histological changes in selected regions of the mouse gut. In order to increase the efficiency of scoring, Definiens Developer software was used to devise an entirely automated method to quantify histological ...[more]