Exploring the structural requirements of collagen-binding peptides.
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ABSTRACT:
SUBMITTER: Abd-Elgaliel WR
PROVIDER: S-EPMC3637416 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Publications
Exploring the structural requirements of collagen-binding peptides.
Abd-Elgaliel Wael R WR Tung Ching-Hsuan CH
Biopolymers 20130401 2
Collagen synthesis and tissue remodeling are involved in many diseases; therefore, collagen-specific binding agents have been developed to study collagen changes in various tissues. Based on a recently reported collagen binding peptide, which contains unnatural biphenylalanine (Bip) amino acid residue, constructs with various structure variations were synthesized to explore the contributions of unnatural Bip residue, conformational restrain, and amino acid sequence in collagen recognition. Their ...[more]
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