Ontology highlight
ABSTRACT:
SUBMITTER: Burgara-Estrella A
PROVIDER: S-EPMC3640520 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Burgara-Estrella Alexel A Díaz Ivan I Rodríguez-Gómez Irene M IM Essler Sabine E SE Hernández Jesús J Mateu Enric E
Viruses 20130211 2
This work describes peptides from non-structural proteins (nsp) of porcine reproductive and respiratory syndrome virus (PRRSV) predicted as potential T cell epitopes by bioinfornatics and tested for their ability to induce IFN-γ and IL-10 responses. Pigs immunized with either genotype 1 or genotype 2 PRRSV attenuated vaccines (n=5/group) and unvaccinated pigs (n = 4) were used to test the peptides. Swine leukocyte antigen haplotype of each pig was also determined. Pigs were initially screened fo ...[more]